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Oncotic pressure, or colloid osmotic-pressure, is a type of osmotic pressure induced by the plasma proteins, notably albumin, [1] in a blood vessel's plasma (or any other body fluid such as blood and lymph) that causes a pull on fluid back into the capillary.
Cardiogenic pulmonary edema is caused by increased hydrostatic pressure causing increased fluid in the pulmonary interstitium and alveoli. Noncardiogenic causes are associated with the oncotic pressure as discussed above causing malfunctioning barriers in the lungs (increased microvascular permeability). [12]
The Starling principle holds that fluid movement across a semi-permeable blood vessel such as a capillary or small venule is determined by the hydrostatic pressures and colloid osmotic pressures (oncotic pressure) on either side of a semipermeable barrier that sieves the filtrate, retarding larger molecules such as proteins from leaving the blood stream.
Edema may be described as pitting edema or non-pitting edema. [32] Pitting edema is when, after pressure is applied to a small area, the indentation persists after the release of the pressure. Peripheral pitting edema, as shown in the illustration, is the more common type, resulting from water retention.
A chest x-ray showing pulmonary edema with bilateral pleural effusions. Along with: Elevations in brain-natriuretic peptide (BNP) or N-terminal (NT)-pro BNP. Evidence of cardiovascular system changes (tachycardia, hypertension, widened pulse pressure, jugular venous distension, peripheral edema) Evidence of fluid overload.
Negative-pressure pulmonary edema (NPPE), also known as Postobstructive Pulmonary Edema, is a clinical phenomenon that results from the generation of large negative pressures in the airways during attempted inspiration against some form of obstruction of the upper airways.
Pulmonary edema: the loss of proteins from blood plasma and the consequent fall in oncotic pressure causes an abnormal accumulation of liquid in the lungs causing hypoxia and dyspnoea. Hypothyroidism : deficiency of the thyroglobulin transport protein thyroxin (a glycoprotein that is rich in iodine and is found in the thyroid gland) due to ...
Increase hydrostatic pressure in vessels: left ventricular heart failure, Decrease oncotic pressure in blood vessels: Cirrhosis (Cirrhosis leads to hypoalbuminemia and decreasing of colloid oncotic pressure in plasma that causes edema) Nephrotic syndrome (also due to hypoalbuminemia caused by proteinuria). Malnutrition (hypoalbuminism)