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CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
The main treatment for acral erythema is discontinuation of the offending drug, and symptomatic treatment to provide analgesia, lessen edema, and prevent superinfection. However, the treatment for the underlying cancer of the patient must not be neglected. Often, the discontinued drug can be substituted with another cancer drug or cancer treatment.
Atrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [ 11 ] [ 12 ] It often begins as short periods of abnormal beating , which become longer or continuous over time. [ 4 ]
Itchy skin [15] Night sweats [15] Unexplained weight loss of at least 10% of the person's total body mass in six months or less [15] Low-grade fever. [15] Fatigue (lassitude) [15] Systemic symptoms such as fever, night sweats, and weight loss are known as B symptoms; thus, presence of these indicate that the person's stage is, for example, 2B ...
A more recent treatment for severe Raynaud's is the use of botulinum toxin. The 2009 article [ 37 ] studied 19 patients ranging in age from 15 to 72 years with severe Raynaud's phenomenon of which 16 patients (84%) reported pain reduction at rest; 13 patients reported immediate pain relief, three more had gradual pain reduction over 1–2 months.
What they look like: Chiggers, a type of small mite, typically leave clusters of bites that are often very itchy. In many cases, chigger bites appear as small, red and itchy bumps. Sometimes, they ...
According to a study, most of the people who experience pruritus daily have increased itching sensations and other associated symptoms during the night. Most studies reveal that senile pruritus is more common in men than women. [3] Common symptoms of senile pruritus include: [3] pain; heat sensation; cold sensation; bumps, blisters or spots ...