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Hypericum perforatum, commonly known as St John's wort (sometimes perforate St John's wort or common St John's wort), is a flowering plant in the family Hypericaceae.It is a perennial plant that grows up to 1 metre (3 ft 3 in) tall, with many yellow flowers that have clearly visible black glands around their edges, long stamens (male reproductive organs), and three pistils (female reproductive ...
Some chemicals found in trace amounts in food, as well as some dietary supplements, have been shown to inhibit 5-LOX; these include baicalein, caffeic acid, curcumin, [3] hyperforin and St John's wort. [8] [9] [10]
Hypericin is a naphthodianthrone, an anthraquinone derivative which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort). [2] [3] Hypericin is believed to act as an antibiotic, antiviral [2] and non-specific kinase inhibitor.
Common St. John's-wort (H. perforatum) has long been used in traditional medicine as an extract to treat depression. [15] H. perforatum is the most commonly used species – especially in Europe – as an herbal substitute for prescription drugs to treat depression, and is also sold as a dietary supplement . [ 15 ]
Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort). [2] Hyperforin may be involved in the pharmacological effects of St. John's wort, [2] specifically in its antidepressant effects. [3] [4] [5]
Hypericum olympicum, commonly known as the Mount Olympus St. John's wort, [2] [Note 1] is a species of flowering plant in the family Hypericaceae found in the Balkans and Turkey and introduced to western Europe.
Hypericum maculatum, commonly known as imperforate St John's-wort, [1]: 340 [2] or spotted St. Johnswort, [3] is a species of perennial herbaceous flowering plant in the family Hypericaceae. It is native to Europe and Western Asia where it grows in moist meadows.
Hypericum frondosum, the cedarglade St. Johnswort or golden St. John's wort, is a species of flowering plant in the St. John's wort family, Hypericaceae. [ 1 ] [ 2 ] [ 3 ] It is native to the central and southeastern United States in dry, rocky habitats.