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  2. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Another 2015 review called the reductions in mortality and hospitalization conferred by sacubitril/valsartan "striking", but noted that its effects in heart failure people with hypertension, diabetes, chronic kidney disease, and the elderly needed to be evaluated further. [40]

  3. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    People treated with ARBs including valsartan or diuretics are susceptible to conditions of developing low renal blood flow such as abnormal narrowing of blood vessels in the kidney, hypertension, renal artery stenosis, heart failure, chronic kidney disease, severe congestive heart failure, or volume depletion whose renal function is in part ...

  4. Sacubitril - Wikipedia

    en.wikipedia.org/wiki/Sacubitril

    Sacubitril (/ s ə ˈ k juː b ɪ t r ɪ l /; INN) is an antihypertensive drug used in combination with valsartan. The combination drug sacubitril/valsartan, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. [1] It was approved under the FDA's priority review process for use in heart ...

  5. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction. Evidence suggests that a reduction of blood pressure by 5 mmHg can decrease the risk of stroke by 34% and of ischaemic heart disease by 21%.

  6. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    [citation needed] More recently, they have been used for the treatment of heart failure in patients intolerant of ACE inhibitor therapy, in particular candesartan. Irbesartan and losartan have trial data showing benefit in hypertensive patients with type 2 diabetes, [citation needed] and may delay the progression of diabetic nephropathy.

  7. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    People with heart failure, also known as congestive heart failure (CHF), are educated to undertake various non-pharmacological measures to improve symptoms and prognosis. Such measures include: [2] Moderate physical activity, when symptoms are mild or moderate; or bed rest when symptoms are severe. In individuals with heart failure, increasing ...

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