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Starved for oxygen and nutrients, elastic fibers become patchy and smooth muscle cells die. If the disease progresses, syphilitic aortitis leads to an aortic aneurysm. Overall, tertiary syphilis is a rare cause of aortic aneurysms. [3] Syphilitic aortitis has become rare in the developed world with the advent of penicillin treatments after ...
Aortitis is most commonly seen in patients with syphilis, autoimmune vasculitis (giant cell arteritis, Takayasu's arteritis), polymyalgia rheumatica, and rheumatoid arthritis. [2] IgG4-related disease has more recently been identified as a cause of aortitis, and also as a cause of periaortitis (inflammation surrounding the aorta). [3]
By the time people are over the age of 50, Park says “about 1 in 5 of us has herpes type 2,” which causes genital herpes. “And then when we talk about herpes type 1, which causes oral herpes ...
In terms of the cause of aortic regurgitation, is often due to the aortic root dilation (annuloaortic ectasia), which is idiopathic in over 80% of cases, but otherwise may result from aging, syphilitic aortitis, osteogenesis imperfecta, aortic dissection, Behçet's disease, reactive arthritis and systemic hypertension. [1]
A staggering 207,000 syphilis cases were reported in the US in 2022 — an 80% increase since 2018. Syphilis cases soar to highest level in 70 years — CDC sounds alarm over ‘unacceptable’ crisis
Congenital syphilis is still common in the developing world, as many women do not receive antenatal care at all, and the antenatal care others receive does not include screening. [50] [54] It still occasionally occurs in the developed world, as those most likely to acquire syphilis are least likely to receive care during pregnancy. [50]
Syphilis is closely related but distinct from two other subspecies or lineages of treponemal disease, nonsexually transmitted illnesses that have similar symptoms that are known as bejel and yaws ...
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]
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