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Biotin deficiency is a nutritional disorder which can become serious, even fatal, if allowed to progress untreated. It can occur in people of any age, ancestry, or of ...
High-dose biotin (300 mg/day = 10,000 times adequate intake) has been used in clinical trials for treatment of multiple sclerosis, a demyelinating autoimmune disease. [37] [38] The hypothesis is that biotin may promote remyelination of the myelin sheath of nerve cells, slowing or even reversing neurodegeneration. The proposed mechanisms are ...
A good source of protein provides a dog with a balanced and complete profile of amino acids, and is essential for growth, muscle maintenance, and various cellular functions. [36]. In a plant-based dog food, the protein composition can be sourced from a variety of ingredients, such grains, rice, corn, wheat, and/or barley.
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Individual B vitamins are referred to by B-number or by chemical name, such as B 1 for thiamine, B 2 for riboflavin, and B 3 for niacin, [1] [2] while some are more commonly recognized by name than by number, such as pantothenic acid (B 5), biotin (B 7), and folate (B 9). [1]
By Medieval times, dogs were more seen as pets rather than just companions and workers which affected their quality of the diet to include "Besides being fed bran bread, the dogs would also get some of the meat from the hunt. If a dog was sick, he would get better food, such as goat's milk, bean broth, chopped meat, or buttered eggs."
The biotin tag can be used in affinity chromatography together with a column that has avidin (or streptavidin or neutravidin) bound to it, which is the natural ligand for biotin. However, harsh conditions (e.g., 6M GuHCl at pH 1.5) are needed to break the avidin/streptavidin - biotin interaction, which will most likely denature the protein ...