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[34] [35] Bitter oranges (such as the Seville oranges often used in marmalade) can interfere with drugs [38] including etoposide, a chemotherapy drug, some beta blocker drugs used to treat high blood pressure, and cyclosporine, taken by transplant patients to prevent rejection of their new organs. [12] Evidence on sweet oranges is more mixed. [11]
For example, when the blood pressure drug felodipine is taken with grapefruit juice rather than water, levels of the medication in the blood can more than double and result in headache, irregular ...
The pomelo, while not itself toxic, can cause adverse interactions similar to those caused by the grapefruit with a wide range of prescription drugs. These occur by the inhibition of cytochrome P450 -mediated metabolism of prescription drugs including for example some anti-hypertensives , some anticoagulants , some anticancer agents , some anti ...
Grapefruit–drug interactions are common, as the juice contains furanocoumarins that interfere with the metabolism of many drugs. This can prolong and intensify the effects of those drugs, leading to multiple side-effects such as abnormal heart rhythms, bleeding inside the stomach, low blood pressure, difficulty breathing, and dizziness.
A registered dietitian shares the best drinks to support healthy weight management ... like GLP-1 medications, directly reduce blood sugar, which can help people manage both diabetes and weight at ...
With more than 2,500 types of citrus worldwide, it would be a shame to limit your larder to lemons and limes. Luckily, many grocers also stock seasonal stunners like Sumo mandarins, yuzu, and pomelos.
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .
As of 2018, the best available evidence favors low-dose thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. [5] Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of ...