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  2. Fibroblast growth factor 2 - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor_2

    Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. [ 5 ] [ 6 ] It binds to and exerts effects via specific fibroblast growth factor receptor (FGFR) proteins , themselves a family of closely related molecules.

  3. Fibroblast growth factor - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor

    A mitogenic growth factor activity was found in pituitary extracts by Armelin in 1973 [14] and further work by Gospodarowicz as reported in 1974 described a more defined isolation of proteins from cow brain extract which, when tested in a bioassay that caused fibroblasts to proliferate, led these investigators to apply the name "fibroblast ...

  4. Fibroblast growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor_1

    Fibroblast growth factor protein was first purified in 1975, but soon afterwards others using different conditions isolated acidic FGF, Heparin-binding growth factor-1, and Endothelial cell growth factor-1. [7] Gene sequencing revealed that this group was actually the same growth factor and that FGF1 was a member of a family of FGF proteins.

  5. Fibroblast growth factor receptor 2 - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor...

    [5] [6] FGFR2 is a receptor for fibroblast growth factor. FGFR-2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. [7] FGFR family members differ from one another in their ligand affinities and tissue distribution.

  6. Growth factor - Wikipedia

    en.wikipedia.org/wiki/Growth_factor

    A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation. [1] Usually it is a secreted protein or a steroid hormone .

  7. Fibroblast activation protein, alpha - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_activation...

    14089 Ensembl ENSG00000078098 ENSMUSG00000000392 UniProt Q12884 P97321 RefSeq (mRNA) NM_001291807 NM_004460 NM_007986 RefSeq (protein) NP_001278736 NP_004451 NP_032012 Location (UCSC) Chr 2: 162.17 – 162.25 Mb Chr 2: 62.33 – 62.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that ...

  8. Bone growth factor - Wikipedia

    en.wikipedia.org/wiki/Bone_growth_factor

    A bone growth factor is a growth factor that stimulates the growth of bone tissue. [1] [2]Known bone growth factors include insulin-like growth factor-1 (IGF-1), insulin-like growth factor-2 (IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), parathyroid hormone-related peptide (PTHrP), bone morphogenetic proteins (BMPs ...

  9. FIBP - Wikipedia

    en.wikipedia.org/wiki/FIBP

    Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF).

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