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Alzheimer's disease is a progressive disease that triggers brain cell deterioration. Over time, this makes things like remembering, learning, controlling emotions, and even basic tasks difficult ...
Given the widespread impacts of Alzheimer's disease, both basic-science and health funders in many countries support Alzheimer's research at large scales. For example, the US National Institutes of Health program for Alzheimer's research, the National Plan to Address Alzheimer’s Disease, has a budget of US$3.98 billion for fiscal year 2026 ...
It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.
Alzheimer’s usually is a disease of people over age 65 and while simply getting older is the main risk, the APOE gene has long been known to play some role. It comes in three main varieties.
“The APOE-e4 allele is the most important for Alzheimer’s disease risk,” she continued.“About 25% of people in the U.S. have at least one APOE-e4 allele and about 5% have two copies of it ...
Additionally, according to the Alzheimer’s Association and NAC/AARP, 60% of Alzheimer’s disease and dementia caregivers are typically female and are 55 or older. [11] This data emphasizes that African Americans are disproportionately affected by Alzheimer’s disease and other forms of dementia.