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Valsartan is combined with amlodipine or hydrochlorothiazide (HCTZ) (or both) into single-pill formulations for treating hypertension with multiple drugs. [8] [41] [42] [43] Valsartan is also available as the combination valsartan/sacubitril. [40] [44] [45] It is used to treat heart failure with reduced ejection fraction. [45] [46]
Sacubitril (/ s ə ˈ k juː b ɪ t r ɪ l /; INN) is an antihypertensive drug used in combination with valsartan. The combination drug sacubitril/valsartan, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. [1] It was approved under the FDA's priority review process for use in heart ...
Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan .
Entresto helps manage chronic heart failure by reducing the effort necessary for the heart to pump blood around the body. This article explains how much a person with Medicare Part D typically ...
Cardiovascular agents are drugs used to treat diseases associated with the heart or blood vessels. These medications are available for purchase only with a physician’s prescription . They include, but are not limited to, drugs that target hypertension ( antihypertensives ), hyperlipidemia ( antihyperlipidemics ) and blood clotting (blood ...
[citation needed] More recently, they have been used for the treatment of heart failure in patients intolerant of ACE inhibitor therapy, in particular candesartan. Irbesartan and losartan have trial data showing benefit in hypertensive patients with type 2 diabetes , [ citation needed ] and may delay the progression of diabetic nephropathy .
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