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Bronchiectasis without CF is known as non-CF bronchiectasis. Historically, about half of all case of non-CF bronchiectasis were found to be idiopathic , or without a known cause. [ 25 ] However, more recent studies with a more thorough diagnostic work-up have found an etiology in 60 to 90% of patients.
It typically occurs in males and females over the age of 35–40. [1] [3] In 2019 it caused 3.2 million deaths, 80% occurring in lower and middle income countries, [3] up from 2.4 million deaths in 1990. [24] [25] In 2021, it was the fourth biggest cause of death, responsible for approximately 5% of total deaths. [26]
Bronchiolitis obliterans results in worsening shortness of breath, wheezing, and a dry cough.The symptoms can start gradually, or severe symptoms can occur suddenly. [9] [10] These symptoms represent an obstructive pattern that is non-reversible with bronchodilator therapy, and need to be related to various lung insults. [11]
Types of obstructive lung disease include asthma, bronchiectasis, bronchitis and chronic obstructive pulmonary disease (COPD). Although COPD shares similar characteristics with all other obstructive lung diseases, such as the signs of coughing and wheezing , they are distinct conditions in terms of disease onset, frequency of symptoms, and ...
[13] [15] Pneumonia is also the leading cause of death in children less than five years of age in low income countries. [15] The most common cause of pneumonia is pneumococcal bacteria, Streptococcus pneumoniae accounts for 2/3 of bacteremic pneumonias. [16] Invasive pneumococcal pneumonia has a mortality rate of around 20%. [14]
Respiratory disease is a common and significant cause of illness and death around the world. In the US, approximately one billion common colds occur each year. [29] A study found that in 2010, there were approximately 6.8 million emergency department visits for respiratory disorders in the U.S. for patients under the age of 18. [30]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
One study suggests the median age of death for men and women is 42 and 44 years old, respectively, ... bronchiectasis, and meningitis. [13]
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