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  2. Epigenetics of anxiety and stress–related disorders - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_anxiety_and...

    Childhood trauma has been associated with a wide array of mental health disorders such as bipolar disorder, anxiety, post traumatic stress disorder (PTSD), and depression. [40] PTSD Inheritability. Research involving PTSD in those who experienced childhood trauma had a 25% to 60% inheritability rate, which is a relatively low to moderate rate ...

  3. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...

  4. Corticotropin-releasing hormone - Wikipedia

    en.wikipedia.org/wiki/Corticotropin-releasing...

    During chronic stress conditions such as post-traumatic stress disorder (PTSD), blood serum levels of CRH are decreased in combat veterans with PTSD compared to healthy individuals. [9] It is believed that chronic stress enhances the negative feedback inhibition of the HPA axis, resulting in lower CRH levels and HPA function. [10] [11] [12]

  5. Post-traumatic stress disorder - Wikipedia

    en.wikipedia.org/wiki/Post-traumatic_stress_disorder

    Post-traumatic stress disorder (PTSD) [b] is a mental and behavioral disorder [8] that develops from experiencing a traumatic event, such as sexual assault, domestic violence, child abuse, warfare and its associated traumas, natural disaster, traffic collision, or other threats on a person's life or well-being.

  6. Stress in early childhood - Wikipedia

    en.wikipedia.org/wiki/Stress_in_early_childhood

    Children may also exhibit symptoms of anxiety. They may begin to have new fears and nightmares or even paranoia.[19] They may lie to others to avoid situations to cover up their feelings. [30] Most often anxiety in children stems from academic stressors and being overwhelmed with responsibilities with workload. [30]

  7. Activation syndrome - Wikipedia

    en.wikipedia.org/wiki/Activation_syndrome

    In some people, this state change can increase suicidal tendencies, especially in those under age 25 and during the initial weeks of treatment. [2] SSRI-induced activation syndrome is well-accepted by clinicians. [3] It is unclear whether jitteriness/anxiety syndrome predicts either good or poor prognosis (level D). [4]

  8. Stress-related disorders - Wikipedia

    en.wikipedia.org/wiki/Stress-related_disorders

    Stress is wear and tear on the body in response to stressful agents. Hans Selye called such agents: stressors, which are physical, physiological or sociocultural. Stress-related disorders differ from anxiety disorders, and do not constitute a normative concept.

  9. Genetics of post-traumatic stress disorder - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_post-traumatic...

    An individual's potential for onset of many psychological disorders is heavily affected by genetic phenotypes, yet this is not the only contributing factor.Environment plays an important role as well, especially for trauma-based disorders such as PTSD, considering that certain life experiences can trigger the activation of an underlying genetic phenotype which might have been previously ...

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