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Buspirone, sold under the brand name Buspar among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Other medications, like buspirone. As a whole, anxiety meds are some of the most widely used medications in the United States — in 2019, nearly 16 percent of American adults were prescribed some ...
5-HT 1A receptor agonists like buspirone [18] and flesinoxan [19] show efficacy in relieving anxiety [20] and depression. [21] Buspirone and tandospirone are currently approved for these indications in different parts of the world.
Buspirone was originally classified as an azaspirodecanedione, shortened to azapirone or azaspirone due to the fact that its chemical structure contained this moiety, and other drugs with similar structures were labeled as such as well. However, despite all being called azapirones, not all of them actually contain the azapirodecanedione ...
Buspirone can be useful in GAD but not particularly effective in treating phobias, panic disorder or social anxiety disorders. [2] It is a safer option for long-term use as it does not cause dependence like benzodiazepines.
Syncope; Hypotension; Hypertension; Redness and itching of the eyes; Altered taste; Conjunctivitis; Flatulence; Anorexia; Increased appetite; Salivation; Rectal bleeding
Keppra (levetiracetam) – an anticonvulsant drug which is sometimes used as a mood stabilizer and has potential benefits for other psychiatric and neurologic conditions such as Tourette syndrome, anxiety disorder, and Alzheimer's disease; Klonopin – anti-anxiety and anti-epileptic medication of the benzodiazepine class
Buspirone is sometimes used off-label to reduce sexual dysfunction associated with the use of SSRIs. [ 54 ] [ 55 ] [ 56 ] A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion , mirtazapine , tianeptine , agomelatine , tranylcypromine , and moclobemide [ 57 ] [ 58 ] [ 59 ] ).