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Satellite glial cells are small cells that surround neurons in sensory, sympathetic, and parasympathetic ganglia. [19] These cells help regulate the external chemical environment. Like astrocytes, they are interconnected by gap junctions and respond to ATP by elevating the intracellular concentration of calcium ions.
Oligodendrocytes are a type of glial cell, non-neuronal cells in the central nervous system.They arise during development from oligodendrocyte precursor cells (OPCs), [8] which can be identified by their expression of a number of antigens, including the ganglioside GD3, [9] [10] [11] the NG2 chondroitin sulfate proteoglycan, and the platelet-derived growth factor-alpha receptor subunit (PDGF ...
Despite their flattened shape, satellite glial cells contain all common organelles necessary to make cellular products and to maintain the homeostatic environment of the cell. The plasma membrane of SGCs is thin and not very dense, [ 10 ] and it is associated with adhesion molecules, [ 11 ] receptors for neurotransmitters and other molecules ...
Schwann cells: The PNS equivalent of oligodendrocytes, they help maintain axons and form myelin sheaths in the PNS. [5] Satellite glial cell: Line the surface of neuron cell bodies in ganglia (groups of nerve body cells bundled or connected together in the PNS) [9] Enteric glia: Found in the enteric nervous system, within the gastrointestinal ...
Aquaporins are membrane-bound channels and regulate the flux of water into and out of cells. Relative to simple diffusion, they increases water permeability 3– to 10-fold. [ 11 ] The two types of aquaporins expressed in the CNS are aquaporin-1, which is expressed by specialized epithelial cells of the choroid plexus , and aquaporin-4 (AQP4 ...
Different glial cells project cytoplasmic processes. In the brain, the processes of astrocytes form terminal endfeet, foot processes that help to form protective barriers in the brain. In the kidneys specialised cells called podocytes extend processes that terminate in podocyte foot processes that cover capillaries in the nephron.
The key cellular components of the neuroimmune system are glial cells, including astrocytes, microglia, and oligodendrocytes. [1] [2] [5] Unlike other hematopoietic cells of the peripheral immune system, mast cells naturally occur in the brain where they mediate interactions between gut microbes, the immune system, and the central nervous system as part of the microbiota–gut–brain axis.
During periods in which glial cell formation is discouraged, neural stem cells have the option to remain pluripotent or switch pathway lineages and begin forming neurons during neurogenesis. If neuron development is instructed, neurogenic factors, i.e. BMPs , [ 8 ] are present to induce expression of proneural transcription factors like ...