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Micrograph showing gliosis in the cerebellum. Reactive astrocytes on the left display severe proliferation and domain overlap. Reactive astrogliosis is the most common form of gliosis and involves the proliferation of astrocytes, a type of glial cell responsible for maintaining extracellular ion and neurotransmitter concentrations, modulating synapse function, and forming the blood–brain ...
MRI image: Leukoaraiosis in a 90-year-old patient with cerebral atrophy. Head CT showing periventricular white matter lesions. Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles. It is often seen in aged individuals, but sometimes in young adults.
These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) [1] [2] or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. [2]
Simultaneous suppression of cerebrospinal fluid and white matter by two inversion times. [13] High signal of multiple sclerosis plaques (pictured). [13] Diffusion weighted (DWI) Conventional: DWI: Measure of Brownian motion of water molecules. [14] High signal within minutes of cerebral infarction (pictured). [15] Apparent diffusion coefficient ...
Using high field MRI system, with several variants several areas show lesions, and can be spacially classified in infratentorial, callosal, juxtacortical, periventricular, and other white matter areas. [21] Other authors simplify this in three regions: intracortical, mixed gray-white matter, and juxtacortical. [22]
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields , magnetic field gradients, and radio waves to form images of the organs in the body.
White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
Some more specialized diffusion MRI techniques such as diffusion kurtosis imaging (DKI) have also been shown to predict the response of cancer patients to chemotherapy treatment. [43] The principal application is in the imaging of white matter where the location, orientation, and anisotropy of the tracts can be measured.