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Ryuzo Yanagimachi (柳町 隆造, Yanagimachi Ryūzō, August 27, 1928 – September 27, 2023) was a Japanese-born, American-based scientist. He made numerous key contributions to the study of mammalian fertilization, and he was also a pioneer in the cloning field.
The Japanese house mouse or Japanese wild mouse (Mus musculus molossinus) is a type of house mouse that originated in Japan. Genetically, it is a hybrid between the southeastern Asian house mouse ( M. m. castaneus ) and the eastern European house mouse ( M. m. musculus ).
Cumulina (October 3, 1997 - May 5, 2000), a mouse, was the first animal cloned from adult cells that survived to adulthood. She was cloned using the Honolulu technique developed by "Team Yana", the Ryuzo Yanagimachi research group at the former campus of the John A. Burns School of Medicine located at the University of Hawai'i at Mānoa.
In 1986, the first mouse was cloned in the Soviet Union from an embryo cell. [60] The first mouse from adult cells, Cumulina, was born in 1997 at the University of Hawaiʻi at Mānoa in the laboratory of Ryuzo Yanagimachi using the Honolulu technique. In 2008 Japanese scientists created a cloned mouse from a dead mouse that had been frozen for ...
After an eight-year project involving the use of a pioneering cloning technique, Japanese researchers created 25 generations of healthy cloned mice with normal lifespans, demonstrating that clones are not intrinsically shorter-lived than naturally born animals.
The Vacanti mouse. The Vacanti mouse was a laboratory mouse (circa 1996) [1] that had what looked like a human ear grown on its back. The "ear" was actually an ear-shaped cartilage structure grown by seeding cow cartilage cells into biodegradable ear-shaped mold and then implanted under the skin of the mouse, with an external ear-shaped splint to maintain the desired shape.
The genetically modified mouse in which a gene affecting hair growth has been knocked out (left) shown next to a normal lab mouse. A genetically modified mouse, genetically engineered mouse model (GEMM) [1] or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques.
The first recorded knockout mouse was created by Mario R. Capecchi, Martin Evans, and Oliver Smithies in 1989, for which they were awarded the 2007 Nobel Prize in Physiology or Medicine. Aspects of the technology for generating knockout mice, and the mice themselves have been patented in many countries by private companies.