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Chronic liver disease (including chronic hepatitis [2]) Pregnancy; Polycythemia; Thyrotoxicosis; Rheumatoid arthritis (especially in patients with polycythaemia) [3] Eczema and psoriasis; Deep telangiectasias; Coxsackievirus A infection (Hand, foot and mouth disease) [4] Rocky Mountain spotted fever [4] Secondary syphilis [4] Kawasaki disease
The spots derive their name from the fact that they were once incorrectly believed to be caused by liver problems, but they are physiologically unrelated to the liver, save for a similar color. [6] From the age of 40, the skin is less able to regenerate from sun exposure, and liver spots are very common in this age group, particularly in those ...
Tinea nigra, also known as superficial phaeohyphomycosis and Tinea nigra palmaris et plantaris, [2] is a superficial fungal infection, a type of phaeohyphomycosis rather than a tinea, that causes usually a single 1–5 cm dark brown-black, non-scaly, flat, painless patch on the palms of the hands and the soles of the feet of healthy people. [1]
PCT is a chronic condition, with external symptoms often subsiding and recurring as a result of multiple factors. In addition to the skin lesions, chronic liver disease is very common in patients with sporadic PCT. This involves hepatic fibrosis (scarring of the liver), and inflammation.
Like liver spots, seborrheic keratoses are seen more often as people age. [4] The tumours (also called lesions) appear in various colours, from light tan to black. They are round or oval, feel flat or slightly elevated, like the scab from a healing wound, and range in size from very small to more than 2.5 centimetres (1 in) across. [5] They are ...
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [ 2 ] such as the posterior and lateral folds of the neck , the armpits , groin , navel , forehead and other areas.
Keratolysis exfoliativa (also known as"lamellar dyshidrosis", [1] "recurrent focal palmar peeling", [2] "recurrent palmar peeling" [1]: 212 [2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet.
Other causes include: infiltrative liver diseases, granulomatous liver disease, abscess, amyloidosis of the liver and peripheral arterial disease. Mild elevation of ALP can be seen in liver cirrhosis, hepatitis, and congestive cardiac failure. Transient hyperphosphataemia is a benign condition in infants, and can reach normal level in 4 months.