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  2. Clinical trials on glucosamine and chondroitin - Wikipedia

    en.wikipedia.org/wiki/Clinical_trials_on...

    In a follow-up study in 2008, 572 patients from the GAIT trial continued their supplementation for 2 years. After 2 years of supplementation with glucosamine and chondroitin sulfate, alone or in combination, there was no benefit in slowing the loss of cartilage, in terms of joint space width, when compared to a placebo or celecoxib. [29]

  3. Glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Glycosaminoglycan

    Members of the glycosaminoglycan family vary in the type of hexosamine, hexose or hexuronic acid unit they contain (e.g. glucuronic acid, iduronic acid, galactose, galactosamine, glucosamine). They also vary in the geometry of the glycosidic linkage. Examples of GAGs include:

  4. Glucosamine - Wikipedia

    en.wikipedia.org/wiki/Glucosamine

    As the formation of glucosamine-6-phosphate is the first step for the synthesis of these products, glucosamine may be important in regulating their production; however, the way that the hexosamine biosynthesis pathway is actually regulated, and whether this could be involved in contributing to human disease remains unclear. [17]

  5. Chondroitin sulfate - Wikipedia

    en.wikipedia.org/wiki/Chondroitin_sulfate

    Chemical structure of one unit in a chondroitin sulfate chain. Chondroitin-4-sulfate: R 1 = H; R 2 = SO 3 H; R 3 = H. Chondroitin-6-sulfate: R 1 = SO 3 H; R 2, R 3 = H.. Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) [1] composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid).

  6. Joint stiffness - Wikipedia

    en.wikipedia.org/wiki/Joint_stiffness

    Joint stiffness may be either the symptom of pain on moving a joint, the symptom of loss of range of motion or the physical sign of reduced range of motion. Pain on movement is commonly caused by osteoarthritis, often in quite minor degrees, and other forms of arthritis. It may also be caused by injury or overuse and rarely by more complex ...

  7. Judge approves multimillion-dollar Realtor settlement ...

    www.aol.com/finance/judge-approves-realtor...

    A federal judge gave a green light to the National Association of Realtors’ settlement, paving the way for an overhaul of the way people buy and sell their homes in the United States.. On ...