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Liver tumors (also known as hepatic tumors) are abnormal growth of liver cells on or in the liver. Several distinct types of tumors can develop in the liver because the liver is made up of various cell types. [1] Liver tumors can be classified as benign (non-cancerous) or malignant (cancerous) growths.
Certain benign liver tumors, such as hepatocellular adenoma, may sometimes be associated with coexisting malignant HCC. Evidence is limited for the true incidence of malignancy associated with benign adenomas; however, the size of hepatic adenoma is considered to correspond to risk of malignancy and so larger tumors may be surgically removed.
A liver metastasis is a malignant tumor in the liver that has spread from another organ that is affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary liver ...
When imaging the liver with ultrasound, large lesions are likely to be HCC (e.g., a mass greater than 2 cm has more than 95% chance of being HCC).Given the blood flow to the liver, HCC would be most visible when the contrast flows through the arteries of the liver (also called the arterial phase) rather than when the contrast flows through the ...
It is the most common liver tumor with a prevalence of 0.4 – 7.4%. It is generally asymptomatic but also can be associated with pain complaints or cytopenia and/or anemia when it is very bulky. It is unique or paucilocular. It can be associated with other types of benign liver tumors.
Hepatoblastoma is a malignant liver cancer occurring in infants and children and composed of tissue resembling fetal liver cells, mature liver cells, or bile duct cells. They usually present with an abdominal mass. The disease is most commonly diagnosed during a child's first three years of life. [1]
Adenoviruses can lead to tumors in rodent models but do not cause cancer in humans; however, they have been exploited as delivery vehicles in gene therapy for diseases such as cystic fibrosis and cancer. [15] Simian virus 40 (SV40), a polyomavirus, can cause tumors in rodent models but is not oncogenic in humans. [16]
Large hepatic adenomas have a tendency to rupture and bleed massively inside the abdomen. If not treated, there is a 30% risk of bleeding. [3] Bleeding may lead to hypotension, tachycardia, and sweating (diaphoresis). [citation needed] Hepatic adenomas are associated with glycogen storage diseases, type 1 diabetes, as well as anabolic steroid use.
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