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Medications that kill rapidly dividing cells or blood cells can reduce the number of platelets in the blood, which can result in bruises and bleeding. Extremely low platelet counts may be temporarily boosted through platelet transfusions and new drugs to increase platelet counts during chemotherapy are being developed.
HDC aims to increase drug concentrations within the tumor microenvironment by using dosages. This increased dosage helps drugs penetrate into the tumor [12] overcoming obstacles like vasculature and interstitial pressure. The improved availability of drugs allows for distribution throughout the tumor mass reaching resistant cancer cells that ...
Iatrogenic causes of pancytopenia include chemotherapy for malignancies if the drug or drugs used cause bone marrow suppression. Rarely, drugs (antibiotics, blood pressure medication, heart medication) can cause pancytopenia. For example, the antibiotic chloramphenicol can cause pancytopenia in some individuals. [1]
The symptoms of TACO can include shortness of breath , low blood oxygen levels , leg swelling (peripheral edema), high blood pressure (hypertension), and a high heart rate (tachycardia). [ 3 ] It can occur due to a rapid transfusion of a large volume of blood but can also occur during a single red blood cell transfusion (about 15% of cases). [ 2 ]
High blood pressure emergency symptoms. Headaches and nosebleeds can be symptoms of a hypertensive emergency or crisis. If your blood pressure is 180/120 mm Hg or higher and you have these ...
To get continuous infusion chemo (over 24 hours or longer) To get nutrition; To get frequent treatments; To get treatments at home; To get long-term therapy (over many months or even longer) To get drugs that can cause serious damage to skin and muscle tissue if they leak outside a vein (these drugs are known as vesicants).
The narrowing of blood vessels leads to an increase in peripheral resistance, thereby elevating blood pressure. While vasoconstriction is a normal and essential regulatory mechanism for maintaining blood pressure and redistributing blood flow during various physiological processes, its dysregulation can contribute to pathological conditions.
The link between dehydration and blood pressure. Dehydration can sometimes cause low blood pressure that can lead to fainting, but not drinking enough water also can result in high blood pressure ...