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The cardiac troponins T and I which are released within 4–6 hours of an attack of MI and remain elevated for up to 2 weeks, have nearly complete tissue specificity and are now the preferred markers for assessing myocardial damage. [14] Heart-type fatty acid binding protein is another marker, used in
It is a useful marker in the laboratory diagnosis of heart attack. [2] It occurs in different plasma concentration but the same circumstances as troponin T - either test can be performed for confirmation of cardiac muscle damage and laboratories usually offer one test or the other. [3]
Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
A positive result is evident from an inducible myocardial perfusion defect. Cost and availability mean that its use is often confined to patients with intermediate pre-test probability, [ 24 ] but it has been shown to reduce unnecessary angiography compared with guidelines-directed care.
Duke Treadmill Score is one of the tools for predicting the risk of ischemia or infarction in the heart muscle. [1] The calculation is done based on the information obtained from an exercise test by this formula: [citation needed] [exercise duration by Bruce protocol] - [ 5 × (maximal ST elevation or depression)] - [4 × (treadmill angina index)]
Coronary arteries deliver oxygen-rich blood to the heart muscle. [5] Reduced blood flow to the heart associated with coronary ischemia can result in inadequate oxygen supply to the heart muscle. [6] When oxygen supply to the heart is unable to keep up with oxygen demand from the muscle, the result is the characteristic symptoms of coronary ...
Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscle tissues, the others being skeletal muscle and smooth muscle. It is an involuntary, striated muscle that constitutes the main tissue of the wall of the heart .