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Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.
In addition to the added potency, the drug has a “low cost,” which leads drug dealers to mix fentanyl with drugs like “heroin, methamphetamine and cocaine, increasing the likelihood of a ...
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
Cutting or "stepping on" the drug is commonplace, using compounds which simulate ingestion effects, such as Novocain (procaine) producing temporary anesthesia, as many users believe a strong numbing effect is the result of strong and/or pure cocaine, ephedrine or similar stimulants that are to produce an increased heart rate. The normal ...
In New York City, police estimate that 8%, or nearly one in every 10 bags of cocaine sold on the street, contain fentanyl, VICE reported. Here's what you need to know about fentanyl.
The number of fentanyl-related overdose deaths in North Carolina also has increased each year since 2016, according to the state Department of Health and Human Services. Deaths rose from 442 in ...
Because of their effect on the part of the brain that regulates breathing, opioids can cause very slow or stopped breathing, during overdoses, leading to hypoxia [16] or death if left untreated. [1] Hypoxia is typically caused by respiratory depression. [17] [18] The brain uses oxygen to regulate the homeostasis of the body.