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Benzonatate was first made available in the United States in 1958 as a prescription medication for the treatment of cough in individuals over the age of 10. [ 24 ] [ 25 ] There is a variety of prescription opioid -based cough relievers, such as hydrocodone and codeine , but have unwanted side effects and potential of abuse and diversion. [ 22 ]
The FDA is warning that a prescription cough medication, benzonatate, is finding its way into kids' hands — and sending them to the hospital. Here's what to know about the medication.
It also includes drugs which are marketed as cough suppressants or antitussives, but their effectiveness in reducing cough symptoms is unclear or minimal. [ 1 ] [ 2 ] [ 3 ] While they have been used by 10% of American children in any given week, they are not recommended in Canada or the United States in children six years or younger because of ...
Cloperastine or cloperastin, in the forms of cloperastine hydrochloride (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate, is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. [1] [2] [3] It was first introduced in 1972 in Japan, and then in Italy in 1981.
Dibunate is a cough suppressant. [1] As the sodium salt, it has been marketed under the name Becantyl (in the United Kingdom), Becantex (in continental Europe), or Linctussal with a dosage of 20 to 30 mg, as either syrup or tablets. [2] Similar to benzonatate, it is a peripherally acting drug.
It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs. [8] It is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism. [9] Benzyl benzoate is used as a topical acaricide, scabicide, and pediculicide in veterinary hospitals. [10]