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It is available for human use to treat worm infections. In certain countries such as France, it is inexpensive and available OTC (without prescription) [3] under the brand name Fluvermal as an alternative to mebendazole which is not currently sold there. [4]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
The evidence for comparing metronidazole to other alternatives such as mebendazole, tinidazole, or nitazoxanide was felt to be of very low quality. [60] While tinidazole has side effects and efficacy similar to those of metronidazole, it is administered with a single dose.
An alternative to albendazole is mebendazole for at least 3 to 6 months. Surgery is indicated for bigger liver cysts (> 10 cm), cysts at risk of rupture and/or complicated cysts. A laparoscopic approach provides excellent cure rates with minimal morbidity and mortality. [40]
Mebendazole (for most nematode infections) ... triazolopyrimidines and their metal complexes have been looked at as an alternative drug to the existing commercial ...
Alternative agents include mebendazole and albendazole. [10] Successful treatment with ivermectin has also been reported. [2] Another way of avoiding these free-swimming stages of infective larvae, is to wear protective footwear when walking in areas of parasite prominence, and maintain general sanitary practices throughout the day.
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