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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Frances Kathleen Oldham Kelsey CM (née Oldham; July 24, 1914 – August 7, 2015) was a Canadian-American [1] pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding the drug's safety. [2]
In the late 1950s and early 1960s, more than 10,000 children in 46 countries were born with deformities, such as phocomelia, as a consequence of thalidomide use. [75] The severity and location of the deformities depended on how many days into the pregnancy the mother was before beginning treatment, with the time-sensitive window occurring ...
‘The thalidomide tragedy is a dark chapter in the history of our nation and the world’ Australia to issue national apology to citizens affected by ‘Thalidomide birth defects’ Skip to main ...
Australia will issue a national apology to all citizens affected by the "Thalidomide tragedy", Prime Minister Anthony Albanese said on Monday, more than half a century after babies were born with ...
A class-action lawsuit by Australian and New Zealand thalidomide survivors against the drug’s British distributor Diageo Scotland Ltd. was settled a decade ago for 89 million Australian dollars ...
Other effects also seen with thalidomide exposure included deformed eyes and hearts, deformed alimentary and urinary tracts, blindness and deafness. [6] The thalidomide tragedy marked a turning point in toxicity testing, as it prompted United States and international regulatory agencies to develop systematic toxicity testing protocol.
During the late 1950s and early 1960s, doctors across the world routinely prescribed thalidomide to pregnant women in attempts to ease nausea. Unbeknownst to anyone taking or prescribing the new ...