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Bumetanide, sold under the brand name Bumex among others, is a medication used to treat swelling and high blood pressure. [2] This includes swelling as a result of heart failure, liver failure, or kidney problems. [2] It may work for swelling when other medications have not. [2] For high blood pressure it is not a preferred treatment. [2]
[17] [18] One guideline recommends memantine or an AChE inhibitor be considered in people in the early-to-mid stage of dementia. [ 19 ] Memantine has been associated with a modest improvement; [ 20 ] with small positive effects on cognition , mood, behavior, and the ability to perform daily activities in moderate-to-severe Alzheimer's disease.
These side effects arise in approximately 10–20% of users, are mild to moderate in severity, and can be managed by slowly adjusting medication doses. [192] Less common secondary effects include muscle cramps , decreased heart rate ( bradycardia ), decreased appetite and weight, and increased gastric acid production.
One, bumetanide, has been outlined as a potential treatment candidate for some people who are genetically predisposed to Alzheimer’s in a new study published in the journal, Nature Ageing.
People who maintain or start physical activity of any intensity after receiving a dementia diagnosis may be at a decreased risk for all-cause mortality, a new study suggests.
Dementia-like symptoms have been found in some individuals who have been exposed to glucocorticoid medication, often dispensed in the form of asthma, arthritis, and anti-inflammatory steroid. [2] The term "steroid dementia" was coined by Varney et al. (1984) in reference to the effects of long-term glucocorticoid use in 1,500 patients. [3]
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