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2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

   www.aol.com/tadalafil-ultimate-guide-dosages...

   In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours. As a long-lasting ED medication, tadalafil is only recommended for use one time per day.

3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   According to a 2008 review of studies on tadalafil, 15 percent of men who used this medication at its highest recommended dose (20 milligrams) experienced headaches.

4. Is It Safe to Take Cialis Daily? - AOL

   www.aol.com/safe-cialis-daily-115900442.html

   Unlike other ED medications, such as Viagra® (sildenafil) and Levitra® (vardenafil), which work for four to five hours per dose, Cialis® (which contains the active ingredient tadalafil) is a ...

5. Macitentan/tadalafil - Wikipedia

   en.wikipedia.org/wiki/Macitentan/tadalafil

   Macitentan/tadalafil, sold under the brand name Opsynvi, is a fixed dose combination medication used for the treatment of pulmonary arterial hypertension. [ 3 ] [ 6 ] It contains macitentan , an endothelin receptor antagonist (ERA); and tadalafil , a phosphodiesterase 5 (PDE5) inhibitor .

6. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   Tadalafil is not recommended in people taking nitrovasodilators such as nitroglycerin, as this may result in a serious drop in blood pressure. [8] Tadalafil is a PDE 5 inhibitor which increases blood flow to the penis. [8] It also dilates blood vessels in the lungs, which lowers the pulmonary artery pressure. [8]

7. Discovery and development of phosphodiesterase 5 inhibitors

   en.wikipedia.org/wiki/Discovery_and_development...

   This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window. Tadalafil is more bioavailable (80%) than sildenafil (40%) and vardenafil (15%) but it has a slow absorption, or about 2 hours compared to 50 minutes of sildenfil. Vardenafil is most known for its potency. [24]

8. Got Headaches from Viagra or Cialis? Here's Why & How to Treat It

   www.aol.com/got-headaches-viagra-cialis-heres...

   Headaches are a common side effect of ED medications such as sildenafil (the active ingredient in Viagra), tadalafil (Cialis) and vardenafil (Levitra), with about 25 percent of men prescribed ...

9. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

   www.aol.com/ed-pill-guide-everything-know...

   Tadalafil. The active ingredient in Cialis, tadalafil is a long-lasting medication that can provide relief from ED for up to 36 hours. Vardenafil. The active ingredient in Levitra, vardenafil can ...