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Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems. [ 1 ] [ 2 ] [ 3 ] The word " lipidome " is used to describe the complete lipid profile within a cell, tissue, organism, or ecosystem and is a subset of the " metabolome " which also includes other major classes of biological molecules (such as ...
Biomarker discovery is a medical term describing the process by which biomarkers are discovered. Many commonly used blood tests in medicine are biomarkers. There is interest in biomarker discovery on the part of the pharmaceutical industry; blood-test or other biomarkers could serve as intermediate markers of disease in clinical trials, and as possible drug targets.
Nivolumab, sold under the brand name Opdivo, is an anti-cancer medication used to treat a number of types of cancer. [2] This includes melanoma, lung cancer, malignant pleural mesothelioma, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, urothelial carcinoma, colon cancer, esophageal squamous cell carcinoma, liver cancer, gastric cancer, and esophageal or gastroesophageal ...
LIPID MAPS (Lipid Metabolites and Pathways Strategy) is a web portal designed to be a gateway to Lipidomics resources. The resource has spearheaded a classification of biological lipids, dividing them into eight general categories. [1] LIPID MAPS provides standardised methodologies for mass spectrometry analysis of lipids, e.g. [2] [3] [4]
Lipidomics is a research field that studies the pathways and networks of cellular lipids in biological systems (i.e., lipidomes) on a large scale. It involves the identification and quantification of the thousands of cellular lipid molecular species and their interactions with other lipids, proteins, and other moieties in vivo.
Lipidome is a term coined in the context of omics in modern biology, within the field of lipidomics. [2] It can be studied using mass spectrometry and bioinformatics as well as traditional lab-based methods. [3] [4] The lipidome of a cell can be subdivided into the membrane-lipidome and mediator-lipidome. [5]
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