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Organophosphate poisoning is poisoning due to organophosphates (OPs). [4] Organophosphates are used as insecticides , medications, and nerve agents . [ 4 ] Symptoms include increased saliva and tear production, diarrhea , vomiting, small pupils , sweating, muscle tremors, and confusion. [ 2 ]
Organophosphate insecticides are acetylcholinesterase inhibitors, which disrupt the transmission of nerve signals in exposed organisms, with fatal results. The risk of human death through organophosphate poisoning [32] was obvious from the start and led to efforts to lower toxicity against mammals while not reducing efficacy against insects ...
The disorder may contribute to the chronic multisymptom illnesses of the Gulf War veterans [3] [4] as well as aerotoxic syndrome (especially tricresyl phosphate poisoning) The exact cause of the syndrome is unknown, although it has been associated with inhibition of patatin-like phospholipase domain-containing protein 6 (PNPLA6, aka neuropathy ...
Variants with P=S double bonds were developed as insecticides because of their reduced mammalian toxicity. The phosphorothioate P=S bond is converted to the toxic P=O bond in the target insect. Similar oxidative conversion in mammals is slower, conferring lower toxicity in mammals.
Organophosphorus chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus. [1] They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment.
Organophosphate nerve agents (3 C, 5 P) Organophosphorohalidates (1 C, 1 P) ... Organophosphate poisoning; Organophosphate-induced delayed neuropathy; Oxon (chemical) P.