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Cryptorchidism, also known as undescended testis, is the failure of one or both testes to descend into the scrotum. The word is from Ancient Greek κρυπτός (kryptos) ' hidden ' and ὄρχις (orchis) ' testicle '. It is the most common birth defect of the male genital tract. [1]
This can be due to: One testicle not descending into the scrotum during normal embryonic or fetal development (3–4% of 'normal' live births), also known as undescended testis or cryptorchidism. In this case the testis is within the abdominal cavity, somewhere along the normal route of descent – most commonly, within the inguinal canal.
Cryptorchidism, or "undescended testicles", is when the testicle does not descend into the scrotum of an infant boy. [30] Testicular enlargement is an unspecific sign of various testicular diseases, and can be defined as a testicular size of more than 5 cm × 3 cm (short axis). [42]
Typical features include undescended testes (cryptorchidism) and the presence of a small, underdeveloped uterus in an XY infant or adult. This condition is usually caused by deficiency of fetal anti-Müllerian hormone (AMH) effect due to mutations of the gene for AMH or the anti-Müllerian hormone receptor , but may also be as a result of ...
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