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A woman smoking crack cocaine in San Francisco, California, in December 2005. Crack cocaine is commonly used as a recreational drug. Effects of crack cocaine include euphoria, [11] supreme confidence, [12] loss of appetite, [11] insomnia, [11] alertness, [11] increased energy, [11] a craving for more cocaine, [12] and potential paranoia (ending ...
A woman smoking crack cocaine "Rocks" of crack cocaine. Crack is usually smoked in a glass pipe, and once inhaled, it passes from the lungs directly to the central nervous system, producing an almost immediate "high" that can be very powerful – this initial crescendo of stimulation is known as a "rush". This is followed by an equally intense ...
Trituration of the free base from cocaine hydrochloride (or "cooking") is done by dissolving the cocaine hydrochloride in water over constant heat, while simultaneously adding a base (such as baking soda) to form the free base cocaine. The free base of cocaine forms a solid "rock", pieces of which can be smoked directly (crack cocaine). [4]
A popular derivative, crack cocaine is typically smoked. When transformed into its freebase form, crack, the cocaine vapour may be inhaled directly. This is thought to increase bioavailability, but has also been found to be toxic, due to the production of methylecgonidine during pyrolysis. [74] [75] [76]
It is a primary metabolite of cocaine, [1] and is pharmacologically inactive. [2] It is the corresponding carboxylic acid of cocaine, its methyl ester. It is formed in the liver by the metabolism of cocaine by hydrolysis, catalysed by carboxylesterases, and subsequently excreted in the urine. It is readily synthesised by boiling cocaine ...
A series of simultaneous police raids targeting a suspected network of drug dealers in east Kent has led to the arrests of seven people. Officers said they seized heroin, crack cocaine and ecstasy ...
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A Romanian grooming gang has been convicted of raping and sexually abusing ten women in flats across Dundee. The four men and one woman also plied their victims - aged between 16 and 30 - with ...