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Cannabis use during pregnancy should be avoided. [80] There is no known safe dose of cannabis while pregnant and use of cannabis may lead to birth defects, pre-term birth, or low birth weight. [80] Tetrahydrocannabinol (THC), an active ingredient in cannabis, can both cross the placenta and accumulates in high concentrations in breast milk. [81]
Ibuprofen can also worsen asthma. [10] While its safety in early pregnancy is unclear, [8] it appears to be harmful in later pregnancy, so it is not recommended during that period. [11] Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). [8] Ibuprofen is a ...
In a press release issued on Thursday, the federal health agency is requiring labeling changes for nonsteroidal anti-inflammatory drugs, such as pain relievers Aleve and Advil, due to potential ...
Prolonged use of opioids by a pregnant mother can also lead to neonatal withdrawal syndrome. [5] [6] NSAIDs such as ibuprofen should generally be avoided in pregnancy, as there are conflicting reports of birth defects after in utero exposure. However, it is accepted that NSAIDs prevent closure of the fetal ductus arteriosus, which happens ...
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In contrast, paracetamol (acetaminophen) is regarded as being safe and well tolerated during pregnancy, but Leffers et al. released a study in 2010, indicating that there may be associated male infertility in the unborn. [92] [93] Doses should be taken as prescribed, due to risk of liver toxicity with overdoses. [94]
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The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.