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The full chapter can be found on pages 101 to 144 of Volume 1, which contains all (sub)categories of the ICD-9. Volume 2 is an alphabetical index of Volume 1. Both volumes can be downloaded for free from the website of the World Health Organization. See here for a tabular overview of primary, secondary, in situ, and benign neoplasms.
A nervous system tumor is a tumor that arises within the nervous system, either the central nervous system (CNS) or the peripheral nervous system (PNS). [1] [2] Nervous system primary tumors include various types of brain tumor and spinal tumors, such as gliomas, and meningiomas (of the CNS), and schwannomas (of the PNS) and can be either benign or malignant.
CNS metastasis is the spread and proliferation of cancer cells from their original tumour to form secondary tumours in portions of the CNS. [1] Typically, this progression initiates when tumour cells separate from the primary tumour and insert into the bloodstream or the lymph system via intravasation. [2]
A brain metastasis is a cancer that has metastasized (spread) to the brain from another location in the body and is therefore considered a secondary brain tumor. [ 1 ] [ 2 ] The metastasis typically shares a cancer cell type with the original site of the cancer. [ 3 ]
9.1.2 Miscellaneous rare lymphomas in the CNS 9.1.2.1 MALT lymphoma of the dura 9.1.2.2 Other low-grade B-cell lymphomas of the CNS 9.1.2.3 Anaplastic large cell lymphoma (ALK+/ALK−) 9.1.2.4 T-cell lymphomas and NK/T-cell lymphomas 9.2 Histiocytic tumors 9.2.1 Erdheim–Chester disease 9.2.2 Rosai–Dorfman disease 9.2.3 Juvenile xanthogranuloma
Oligoastrocytomas are a subset of brain tumors that present with an appearance of mixed glial cell origin, astrocytoma and oligodendroglioma. [1] However, the term "Oligoastrocytoma" is now considered obsolete by the National Comprehensive Cancer Network [2] stating "the term should no longer be used as such morphologically ambiguous tumors can be reliably resolved into astrocytomas and ...
The approach to management of a CNS PNET is first to obtain detailed imaging through MRI, as well as additional scans of the patient's body (X-ray, CT, PET, even bone marrow biopsies) to look for metastasis or other associated malignancies. The tumor will then need to be biopsied to confirm the diagnosis.
Astrocytoma causes regional effects by compression, invasion, and destruction of brain parenchyma, arterial and venous hypoxia, competition for nutrients, release of metabolic end products (e.g., free radicals, altered electrolytes, neurotransmitters), and release and recruitment of cellular mediators (e.g., cytokines) that disrupt normal parenchymal function. [2]