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The signs and symptoms of Graves' disease generally result from the direct and indirect effects of hyperthyroidism, although they can also be caused by other thyroidal conditions, such as Graves' ophthalmopathy, goitre and pretibial myxedema. These clinical manifestations can involve virtually every system in the body.
If left untreated, more serious complications could result, including birth defects in pregnancy, increased risk of a miscarriage, bone mineral loss [37] and, in extreme cases, death (e.g. indirectly through complications, or through a thyroid storm event). Graves' disease is often accompanied by an increase in heart rate, which may lead to ...
Goiter is the general enlargement of the thyroid that can be associated with many thyroid diseases. The main reason this happens is because of increased signaling to the thyroid by way of TSH receptors to try to make it produce more thyroid hormone. [9] This causes increased vascularity and increase in size (hypertrophy) of the gland. [9]
Heart failure and heart attack may occur. Death may occur despite treatment. [4] Most episodes occur either in those with known hyperthyroidism whose treatment has stopped or become ineffective, or in those with untreated mild hyperthyroidism who have developed an intercurrent illness (such as an infection). [4]
A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. [ 1 ] [ 2 ] A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency . [ 3 ]
These studies add to the growing body of data showing that COVID-19 infection can enhance risk for experiencing adverse cardiac events—heart attack, stroke and death—over time,” explains Dr ...