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Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [ 12 ] [ 16 ] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [ 12 ]
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
Tramadol/paracetamol, also known as tramadol/acetaminophen and sold under the brand name Ultracet among others, is a fixed-dose combination medication used for the treatment of moderate to severe pain. [3] [4] It contains tramadol, as the hydrochloride, an analgesic; and paracetamol an analgesic. [3] [4] It is taken by mouth. [3] [4]
In October 2007 an astute medical interpreter noticed similar neurological symptoms being reported by Spanish-speaking patients seeking treatment from different physicians at the Austin Medical Center, in Austin, Minnesota. [11] Not only did these patients share similar neurological symptoms, they also worked at the same slaughterhouse.
Spinal stenosis is an abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots. [6] Symptoms may include pain, numbness, or weakness in the arms or legs. [1] Symptoms are typically gradual in onset and improve with leaning forward. [1]
Findings from clinical trials in humans have shown these antidepressants can help to reduce pain and functional impairment in central and neuropathic pain conditions. This property of SNRIs might be used to reduce doses of other pain relieving medication and lower the frequency of safety, limited efficacy and tolerability issues. [ 45 ]