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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    34,000 p.a. (a contributory factor to a further 376,000 p.a.) [7] Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood ...

  3. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both ...

  4. Congenital hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Congenital_hemolytic_anemia

    Congenital hemolytic anemia (CHA) is a diverse group of rare hereditary conditions marked by decreased life expectancy and premature removal of erythrocytes from blood flow. Defects in erythrocyte membrane proteins and red cell enzyme metabolism , as well as changes at the level of erythrocyte precursors, lead to impaired bone marrow ...

  5. Fetal hemoglobin - Wikipedia

    en.wikipedia.org/wiki/Fetal_hemoglobin

    Chr. 11 p15.4. Fetal hemoglobin, or foetal haemoglobin (also hemoglobin F, HbF, or α2γ2) is the main oxygen carrier protein in the human fetus. Hemoglobin F is found in fetal red blood cells, and is involved in transporting oxygen from the mother's bloodstream to organs and tissues in the fetus. It is produced at around 6 weeks of pregnancy ...

  6. For people with sickle cell disease, ERs can mean life ... - AOL

    www.aol.com/news/people-sickle-cell-disease-ers...

    It’s a strategy to combat discrimination the 42-year-old photographer of Mesquite, Texas, has developed over a lifetime of managing her sickle cell disease, a rare blood disorder that affects an ...

  7. Antagonistic pleiotropy hypothesis - Wikipedia

    en.wikipedia.org/wiki/Antagonistic_pleiotropy...

    The antagonistic pleiotropy hypothesis (APT) is a theory in evolutionary biology that suggests certain genes may confer beneficial effects early in an organism's life, enhancing reproductive success, while also causing detrimental effects later in life, contributing to the aging process. APT was first proposed in a 1952 paper on the ...

  8. Woman with sickle cell disease celebrates 80th birthday ... - AOL

    www.aol.com/news/woman-sickle-cell-disease...

    McGill is one of the nation’s oldest people with sickle cell disease, living decades past age 52, the life expectancy of someone with the disease, which has a disproportionate effect on Black ...

  9. Sickle cell-beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell-beta_thalassemia

    Sickle cell-beta thalassemia. Sickle cell beta thalassemia. Other names. Sickle cell-β thalassemia. Specialty. Hematology. Sickle cell-beta thalassemia is an inherited blood disorder. The disease may range in severity from being relatively benign and like sickle cell trait to being similar to sickle cell disease. [1][2]

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