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In January 2018, Roche announced that the US Food and Drug Administration (FDA) had granted breakthrough therapy designation for balovaptan in people with autism spectrum disorder (ASD). [3] The FDA granted this based on the results of the adult phase II clinical trial called VANILLA (Vasopressin ANtagonist to Improve sociaL communication in ...
Debamestrocel (growth factor-producing stem cell therapy) – dopaminergic cell replacement therapy [27] FIN-211 – bacteria replacement and gastrointestinal microbiome modulator [28] Levophacetoperane (NLS-3; (R,R)-phacetoperone; methylphenidate reverse ester) – norepinephrine and dopamine reuptake inhibitor and psychostimulant [29] [30]
Vasopressin infusions are in use for septic shock patients not responding to fluid resuscitation or infusions of catecholamines (e.g., dopamine or norepinephrine) to increase the blood pressure while sparing the use of catecholamines. These argipressins have much shorter elimination half-life (around 20 minutes) than synthetic non-arginine ...
The Treatment and Education of Autistic and Related Communication Handicapped Children (TEACCH) philosophy recognizes autism as a lifelong condition and does not aim to cure but to respond to autism as a culture. [2] Core tenets of the TEACCH philosophy include an understanding of the effects of autism on individuals; use of assessment to ...
Autism therapies. A three-year-old with autism points to fish in an aquarium, as part of an experiment (2004) on the effect of intensive shared-attention training on language development. [1] Autism therapies include a wide variety of therapies that help people with autism, or their families. Such methods of therapy seek to aid autistic people ...
Ole Ivar Løvaas (8 May 1927 – 2 August 2010) [1][2] was a Norwegian-American clinical psychologist and professor at the University of California, Los Angeles. He is most well known for his research on what is now called applied behavior analysis (ABA) to teach autistic children through prompts, modeling, and positive reinforcement.
Vasopressin receptor 1A (V1AR), or arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for vasopressin (AVPR1B and AVPR2 being the others), and is present throughout the brain, as well as in the periphery in the liver, kidney, and vasculature. [5] AVPR1A is also known as: V1a vasopressin receptor.
High-functioning autism (HFA) was historically an autism classification to describe a person who exhibited no intellectual disability but otherwise showed autistic traits, such as difficulty in social interaction and communication, as well as repetitive, restricted patterns of behavior. The term is often applied to autistic people who are ...