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Other antimalarials like amodiaquine, halofantrine, and hydroxychloroquine have also been linked to pruritus, albeit less frequently and to a lesser extent. [2] Another class of medications known to occasionally cause itching is known as serotonin reuptake inhibitors. [3] Itching is one of the most frequent adverse effects of opioid therapy. [4]
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. [1] Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain , and while both are unpleasant sensory experiences, their behavioral response patterns are different.
Drug-specific risk factors include the dose, route of administration, duration of treatment, repetitive exposure to the drug, and concurrent illnesses. Host risk factors include age, sex, atopy, specific genetic polymorphisms, and inherent predisposition to react to multiple unrelated drugs (multiple drug allergy syndrome). [ 3 ]
Destruction of the normal protective flora of beneficial bacteria can occur in dogs and horses. [21] [22] Dogs may have side effects that include: joint pain, loss of appetite, vomiting, flatulence (intestinal gas), fungal infections and digestive problems. [23] Like humans, dogs can have a similar side effect related to developing a serious ...
The reaction is also seen in the other diseases caused by spirochetes: Lyme disease, relapsing fever, and leptospirosis. [4] There have been case reports of the Jarisch–Herxheimer reaction accompanying treatment of other infections, including Q fever , bartonellosis , brucellosis , trichinellosis , and African trypanosomiasis .
As it is often the result of scratches, involving contact with other materials, it can be confused with an allergic reaction, when in fact it is the act of being scratched that causes a wheal to appear. These wheals are a subset of urticaria (hives), and appear within minutes, in some cases accompanied by itching. The first outbreak of ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
A chronological relationship of pruritus with one or several life events that can have psychological consequences; Changes during the nighttime; More present during rest or inaction; There is a coupled psychological disorder; Pruritus that could be improved with psychotropic drugs; Pruritus that could be improved by psychotherapies