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Δ 9-tetrahydrocannabinol (THC) Cannabis sativa, scientific drawing from c. 1900 Although the main psychoactive constituent of Cannabis is tetrahydrocannabinol (THC), the plant is known to contain more than 500 compounds, among them at least 113 cannabinoids ; however, most of these "minor" cannabinoids are only produced in trace amounts. [ 10 ]
Medical cannabis (or medical marijuana) refers to the use of cannabis and its constituent cannabinoids, in an effort to treat disease or improve symptoms. Cannabis is used to reduce nausea and vomiting during chemotherapy , to improve appetite in people with HIV/AIDS , and to treat chronic pain and muscle spasms .
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
Female cannabis plants contain at least 113 cannabinoids, [55] including cannabidiol (CBD), thought to be the major anticonvulsant that helps people with multiple sclerosis, [56] and cannabichromene (CBC), an anti-inflammatory which may contribute to the pain-killing effect of cannabis.
Nabiximols (brand name Sativex), an oromucosal spray made of a complex botanical mixture containing cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), and additional cannabinoid and non-cannabinoid constituents from cannabis sativa plants, was approved by Health Canada in 2005, to treat central neuropathic pain in multiple sclerosis, and in ...
More than 80% said they use pot to relax, 68% take it to help them sleep and 63% say cannabis is a form of pain relief. For 53% of respondents, cannabis is a mental health and mood booster, while ...
Nabiximols [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain , spasticity , overactive bladder , and other symptoms of multiple sclerosis ; it was developed by the UK company GW ...
A 2005 meta analysis concluded that adolescent use of cannabis increases the risk of psychosis, and that the risk is dose-related. [48] A 2004 literature review on the subject concluded that cannabis use is associated with a two-fold increase in the risk of psychosis, but that cannabis use is "neither necessary nor sufficient" to cause ...