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A DPD scan is a type of nuclear medicine imaging test which uses radioactive technetium-99m (99m Tc) and 3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) to diagnose cardiac amyloidosis. The radiopharmaceutical is taken up only in patients with ATTR amyloidosis , making it a useful tool to differentiate from AL amyloidosis .
A SAP scan is a type of nuclear medicine imaging test which uses iodine-123 (123 I) and serum amyloid P component (SAP) to diagnose amyloidosis. [ 1 ] [ 2 ] In patients with amyloidosis, large deposits of SAP coat the affected organs, in addition to the low levels normally found in the blood stream. [ 3 ]
The most useful stain in the diagnosis of amyloid is Congo red, which, combined with polarized light, makes the amyloid proteins appear apple-green on microscopy. Also, thioflavin T stain may be used. [22] A number of imaging techniques such as a Nuclear Medicine PYP scan, DPD scan or SAP scan are also in use. [23]
Single-photon emission computed tomography (SPECT, or less commonly, SPET) is a nuclear medicine tomographic imaging technique using gamma rays. [1] It is very similar to conventional nuclear medicine planar imaging using a gamma camera (that is, scintigraphy), [2] but is able to provide true 3D information. This information is typically ...
A rectilinear scanner is an imaging device, used to capture emission from radiopharmaceuticals in nuclear medicine. The image is created by physically moving a radiation detector over the surface of a radioactive patient. It has become obsolete in medical imaging, largely replaced by the gamma camera since the late 1960s. [1] [2] [3]
Gated SPECT is a nuclear medicine imaging technique, typically for the heart in myocardial perfusion imagery. [1] An electrocardiogram (ECG) guides the image acquisition, and the resulting set of single-photon emission computed tomography (SPECT) images shows the heart as it contracts over the interval from one R wave to the next.
20219 Ensembl ENSG00000132703 ENSMUSG00000026542 UniProt P02743 P12246 RefSeq (mRNA) NM_001639 NM_011318 RefSeq (protein) NP_001630 NP_035448 Location (UCSC) Chr 1: 159.59 – 159.59 Mb Chr 1: 172.72 – 172.72 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein ...
MIP Display was invented for use in Nuclear Medicine by Jerold Wallis, MD, in 1988 at Washington University in St. Louis, and subsequently published in IEEE Transactions on Medical Imaging. [2] In the setting of Nuclear Medicine, it was originally called MAP (Maximum Activity Projection). [3] [4]