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The tunica intima (Neo-Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells (and macrophages in areas of disturbed blood flow), [1] [2] and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.
The outer layer, is a thick layer of connective tissue called the tunica externa or adventitia; this layer is absent in the post-capillary venules. [4] The middle layer, consists of bands of smooth muscle and is known as the tunica media. The inner layer, is a thin lining of endothelium known as the tunica intima.
The endothelium is a thin layer of single flat cells that line the interior surface of blood vessels and lymphatic vessels. [1] Endothelium is of mesodermal origin. Both blood and lymphatic capillaries are composed of a single layer of endothelial cells called a monolayer. In straight sections of a blood vessel, vascular endothelial cells ...
The inner layer, tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by a polysaccharide intercellular matrix, surrounded by a thin layer of subendothelial connective tissue interlaced with a number of circularly arranged elastic bands called the internal elastic lamina. A thin membrane of ...
Micrograph showing the internal elastic lamina (thin pink wavy line - image edge mid-left to image edge bottom-centre-left). H&E stain.. The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels.
They are composed of only the tunica intima (the innermost layer of an artery or vein), consisting of a thin wall of simple squamous endothelial cells. [2] They are the site of the exchange of many substances from the surrounding interstitial fluid , and they convey blood from the smallest branches of the arteries ( arterioles ) to those of the ...
As with veins, the arterial wall consists of three layers called tunics, namely the tunica intima, tunica media, and tunica externa, from innermost to outermost. The externa , alternatively known as the tunica adventitia , is composed of collagen fibers and elastic tissue —with the largest arteries containing vasa vasorum , small blood ...
The structure of the vasa vasorum varies with the size, function and location of the vessels. Cells need to be within a few cell-widths of a capillary to stay alive. In the largest vessels, the vasa vasorum penetrates the outer (tunica adventitia) layer and middle (tunica media) layer almost to the inner (tunica intima) layer.