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  2. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline is contraindicated in individuals taking monoamine oxidase inhibitors or the antipsychotic pimozide. Sertraline concentrate contains ethanol and is therefore contraindicated with disulfiram. The prescribing information recommends that treatment of the elderly and patients with liver impairment "must be approached with caution".

  3. Grant management software - Wikipedia

    en.wikipedia.org/wiki/Grant_Management_Software

    Grant management software is a program or application that helps non-profits administer the grant process. Some software is designed to help foundations (known as "grantmakers") to organize, prioritize, and process the grant applications they receive from charities (known as "grantseekers"), as well as simplify oversight of the grants they make.

  4. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    This change appears to remove the antihistaminic properties of the drug. By removing the (R)-enantiomer, the lowest dose of escitalopram becomes more efficacious and faster onset than comparable dose of citalopram, where escitalopram has twice the activity of citalopram and is at least 27 times more potent than the (R)-enantiomer. [6]

  5. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    Post-SSRI sexual dysfunction (PSSD) [64] [65] refers to a set of symptoms reported by some people who have taken SSRIs or other serotonin reuptake-inhibiting (SRI) drugs, in which sexual dysfunction symptoms persist for at least three months [66] [67] [68] after ceasing to take the drug. The status of PSSD as a legitimate and distinct pathology ...

  6. Serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin_reuptake_inhibitor

    A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic ...

  7. Desmethylsertraline - Wikipedia

    en.wikipedia.org/wiki/Desmethylsertraline

    Desmethylsertraline (DMS), also known as norsertraline, is an active metabolite of the antidepressant drug sertraline.Like sertraline, desmethylsertraline acts as a monoamine reuptake inhibitor, and may be responsible for some of its parent's therapeutic benefits; however, the effects of DMS's main activity of increasing serotonin levels via binding to the serotonin transporter appears to be ...

  8. Antidepressant Sertraline taken by Thomas Kingston before ...

    www.aol.com/antidepressant-sertraline-taken...

    The antidepressants taken by Thomas Kingston before he killed himself have ben flagged more than 40 times by coroners, it has been found. The 45-year-old husband of Lady Gabriella Windsor took his ...

  9. Serotonin–dopamine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–dopamine...

    Medifoxamine (Cledial, Gerdaxyl) is an antidepressant that appears to act as an SDRI as well as a 5-HT 2 receptor antagonist. [3] Sibutramine (Reductil, Meridia, Siredia, Sibutrex) is a withdrawn anorectic that itself as a molecule in vitro is an SNDRI but preferentially an SDRI, with 18.3- and 5.8-fold preference for inhibiting the reuptake of serotonin and dopamine over norepinephrine ...