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Triptorelin is used to treat prostate cancer as part of androgen deprivation therapy. [9]Another common use in the United Kingdom is for hormone replacement therapy to suppress testosterone or estrogen levels in transgender people (in conjunction with estradiol valerate for trans women or testosterone for trans men).
Bioidentical hormones were first used for menopausal symptom relief in the 1930s, [2] after Canadian researcher James Collip developed a method to extract an orally active estrogen from the urine of pregnant women and marketed it as the active agent in a product called Emmenin. [3]
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
Tibolone is used in the treatment of menopausal symptoms like hot flashes and vaginal atrophy, postmenopausal osteoporosis, and endometriosis. [1] [20] [11] It has similar or greater effectiveness compared to older menopausal hormone therapy medications, but shares a similar side effect profile.
For women, a drop in estrogen can cause weight gain, particularly in the abdomen (aka menopause belly). For men, low testosterone is linked to an increase in fat mass. Men with obesity are more ...
DHEA can be lower in people with depression and after menopause, and levels tend to decrease as you age. At age 70 to 80 , DHEA levels may be down to 10 to 20 percent of those in a younger person.