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The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The collecting duct system begins in the renal cortex and extends deep into the medulla. As the urine travels down the collecting duct system, it passes by the medullary interstitium which has a high sodium concentration as a result of the loop of Henle's countercurrent multiplier system. [1]: 67
The medullary rays of the cortex contain the proximal straight tubules, the cortical part of the thick ascending limb of the loops of Henle, and the cortical part of the collecting ducts. [72] The cortex is divided into lobules, each of which is a medullary ray in conjunction with connected to it nephrons, and interlobular arteries that pass ...
In the adult, it forms a continuous smooth outer zone with a number of projections (cortical columns) that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts.
The medullary interstitium is the tissue surrounding the loop of Henle in the medulla. It functions in renal water reabsorption by building up a high hypertonicity, which draws water out of the thin descending limb of the loop of Henle and the collecting duct system.
The juxtaglomerular apparatus (also known as the juxtaglomerular complex) is a structure in the kidney that regulates the function of each nephron, the functional units of the kidney.
A cortical lobule (or renal lobule) is a part of a renal lobe. It consists of the nephrons grouped around a single medullary ray , and draining into a single collecting duct . Its near identical parallel is the rectal lobe [ citation needed ] , which is present in the majority of mammals.
reabsorption in medullary collecting ducts: Sodium: Uses Na-H antiport, Na-glucose symport, sodium ion channels (minor) [7] reabsorption (65%, isosmotic) reabsorption (25%, thick ascending, Na-K-2Cl symporter) reabsorption (5%, sodium-chloride symporter) reabsorption (5%, principal cells), stimulated by aldosterone via ENaC: Chloride: Usually ...