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When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin–angiotensin–aldosterone system, to increase blood pressure ...
In the mammalian kidney, they follow two markedly different courses, depending on the location of the glomeruli from which they arise. In the mammalian kidney, about 15% of glomeruli lie close to the boundary between the renal cortex and renal medulla and are known as juxtamedullary glomeruli. The rest are simply undifferentiated cortical ...
The vascular pole is a location of the glomerulus. At the vascular pole, the afferent arterioles and efferent arterioles enter and leave the glomerulus in the Bowman's capsule. The tubular pole is at the other end opposite to the vascular pole.
In nephrons with a long loop of Henle, the efferent arterioles branch, forming straight vessels called vasa recta, which descend into the medulla. The descending vasa recta, ascending vasa recta vessels, and the loop of Henle together form the countercurrent system of the kidney. In the afferent arteriole, blood is supplied at high pressure ...
Juxtaglomerular cells (JG cells), also known as juxtaglomerular granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin. [1] They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) [citation needed] that deliver blood to the glomerulus.
In the kidneys, angiotensin II constricts glomerular arterioles, having a greater effect on efferent arterioles than afferent. As with most other capillary beds in the body, the constriction of afferent arterioles increases the arteriolar resistance, raising systemic arterial blood pressure and decreasing the blood flow. However, the kidneys ...
The afferent arterioles, then, enter Bowman's capsule and end in the glomerulus. From each glomerulus, the corresponding efferent arteriole arises and then exits the capsule near the point where the afferent arteriole enters. Distally, efferent arterioles branch out to form dense plexuses (i.e., capillary beds) around their adjacent renal tubules.
The venous drainage of the kidney large mirrors its arterial supply, except that there are no segmental veins. [4] The stellate veins arise from the capillaries, then drain successively through interlobular veins and interlobar veins until these converge from across the kidney to form the renal vein for that kidney.