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1957: Marvin Minsky, a professor at MIT, invents the confocal microscope, an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation. This technology is a predecessor to today's widely used confocal laser scanning microscope.
The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are the oldest design of microscope and were possibly invented in their present compound form in the 17th century.
It permits rapid switching from viewing one photograph to viewing the other, "blinking" back and forth between the two images taken of the same area of the sky at different times. This allows the user to more easily spot objects in the night sky that have changed position or brightness. It was also sometimes known as a blink microscope.
A two-photon microscope is also a laser-scanning microscope, but instead of UV, blue or green laser light, a pulsed infrared laser is used for excitation. Only in the tiny focus of the laser is the intensity high enough to generate fluorescence by two-photon excitation , which means that no out-of-focus fluorescence is generated, and no pinhole ...
Léon Foucault developed a catadioptric microscope in 1859 to counteract aberrations of using a lens to image objects at high power. [2] In 1876 a French engineer, A. Mangin, invented what has come to be called the Mangin mirror, a concave glass reflector with the silver surface on the rear side of the glass. The two surfaces of the reflector ...
The name "camera lucida" (Latin for 'light chamber') is intended to recall the much older drawing aid, the camera obscura (Latin for 'dark chamber'). There is no optical similarity between the devices. The camera lucida is a lightweight, portable device that does not require special lighting conditions.
1672: Sir Isaac Newton: discovers that white light is a mixture of distinct coloured rays (the spectrum). 1673: Christiaan Huygens: first study of oscillating system and design of pendulum clocks; 1675: Leibniz, Newton: infinitesimal calculus. 1675: Anton van Leeuwenhoek: observes microorganisms using a refined simple microscope.
A comparison microscope is a device used to analyze side-by-side specimens. It consists of two microscopes connected by an optical bridge, which results in a split view window enabling two separate objects to be viewed simultaneously. This avoids the observer having to rely on memory when comparing two objects under a conventional microscope.