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  2. Chirality (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Chirality_(chemistry)

    Many chiral molecules have point chirality, namely a single chiral stereogenic center that coincides with an atom. This stereogenic center usually has four or more bonds to different groups, and may be carbon (as in many biological molecules), phosphorus (as in many organophosphates ), silicon, or a metal (as in many chiral coordination ...

  3. Chirality - Wikipedia

    en.wikipedia.org/wiki/Chirality

    The term "chiral" in general is used to describe the object that is non-superposable on its mirror image. [18] In chemistry, chirality usually refers to molecules. Two mirror images of a chiral molecule are called enantiomers or optical isomers. Pairs of enantiomers are often designated as "right-", "left-handed" or, if they have no bias ...

  4. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    In the CIP or R/S convention, or sequence rule, the configuration, spatial arrangements of ligands/substituents around a chiral center, is labeled as either "R" or "S". [18] [2] This convention is now almost worldwide in use and become a part of the IUPAC (International Union of Pure and Applied Chemistry) rules of nomenclature. In this ...

  5. Stereocenter - Wikipedia

    en.wikipedia.org/wiki/Stereocenter

    A chirality center (chiral center) is a type of stereocenter. A chirality center is defined as an atom holding a set of four different ligands (atoms or groups of atoms) in a spatial arrangement which is non-superposable on its mirror image. Chirality centers must be sp 3 hybridized, meaning that a chirality center can only have single bonds. [5]

  6. Molecular configuration - Wikipedia

    en.wikipedia.org/wiki/Molecular_configuration

    R-S isomerism of thalidomide. Chiral center marked with a star(*). Hydrogen (not drawn) is projecting behind the chiral centre. Enantiomers are molecules having one or more chiral centres that are mirror images of each other. [2] Chiral centres are designated R or S. If the 3 groups projecting towards you are arranged clockwise from highest ...

  7. Absolute configuration - Wikipedia

    en.wikipedia.org/wiki/Absolute_configuration

    are arranged around the chiral center carbon atom. With the hydrogen atom away from the viewer, if the arrangement of the CO→R→N groups around the carbon atom as center is counter-clockwise, then it is the L form. [14] If the arrangement is clockwise, it is the D form. As usual, if the molecule itself is oriented differently, for example ...

  8. Asymmetric carbon - Wikipedia

    en.wikipedia.org/wiki/Asymmetric_carbon

    In stereochemistry, an asymmetric carbon is a carbon atom that is bonded to four different types of atoms or groups of atoms. [1] [2] The four atoms and/or groups attached to the carbon atom can be arranged in space in two different ways that are mirror images of each other, and which lead to so-called left-handed and right-handed versions (stereoisomers) of the same molecule.

  9. Prochirality - Wikipedia

    en.wikipedia.org/wiki/Prochirality

    A face is labeled re if, when looking at that face, the substituents at the trigonal atom are arranged in increasing Cahn-Ingold-Prelog priority order (1 to 2 to 3) in a clockwise order, and si if the priorities increase in anti-clockwise order; note that the designation of the resulting chiral center as S or R depends on the priority of the ...