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  2. List of medicine contamination incidents - Wikipedia

    en.wikipedia.org/wiki/List_of_medicine...

    These changes caused drugs made with tetrazole to be contaminated with N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA), which cause genetic damage and cancer. [20] This contamination was not detected until 2018. The incident, according to medicinal chemist and pharmaceutical industry blogger Dr. Derek Lowe, points to a greater ...

  3. Root cause analysis - Wikipedia

    en.wikipedia.org/wiki/Root_cause_analysis

    In science and engineering, root cause analysis (RCA) is a method of problem solving used for identifying the root causes of faults or problems. [1] It is widely used in IT operations, manufacturing, telecommunications, industrial process control, accident analysis (e.g., in aviation, [2] rail transport, or nuclear plants), medical diagnosis, the healthcare industry (e.g., for epidemiology ...

  4. Drug recall - Wikipedia

    en.wikipedia.org/wiki/Drug_recall

    A drug recall removes a prescription or over-the-counter drug from the market. Drug recalls in the United States are made by the FDA or the creators of the drug when certain criteria are met. When a drug recall is made, the drug is removed from the market and potential legal action can be taken depending on the severity of the drug recall. [1]

  5. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Still used as veterinary drug and as a human antihelminthic in many markets; listed on the WHO List of Essential Medicines. In humans, it was used to treat melanoma before it was withdrawn for agranulocytosis. [29] [30] [31] Levomethadyl acetate: 2003 US Cardiac arrhythmias and cardiac arrest. [2] Lorcaserin (Belviq) 2020 US Increased risk of ...

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  7. Current reality tree (theory of constraints) - Wikipedia

    en.wikipedia.org/wiki/Current_reality_tree...

    Current reality tree example. A CRT begins with a list of problems, known as undesirable effects (UDEs.) These are assumed to be symptoms of a deeper common cause. To take a somewhat frivolous example, a car owner may have the following UDEs: the car's engine will not start; the air conditioning is not working; the radio sounds distorted

  8. Corrective and preventive action - Wikipedia

    en.wikipedia.org/wiki/Corrective_and_preventive...

    A root cause is the identification and investigation of the source of the problem where the person(s), system, process, or external factor is identified as the cause of the nonconformity. The root cause analysis can be done via 5 Whys or other methods, e.g. an Ishikawa diagram.

  9. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Polypharmacy is most commonly defined as the use of five or more medications daily by an individual. [6] However, the definition of polypharmacy is still debated and can vary from two to 11 concurrent medications. [6] Any drug: Cannabis: Amp joint [7] Any drug: Nicotine: Cooler [5] Any β-Carboline containing plant (e.g. Banisteriopsis caapi or ...