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EEG can detect abnormal electrical discharges such as sharp waves, spikes, or spike-and-wave complexes, as observable in people with epilepsy; thus, it is often used to inform medical diagnosis. EEG can detect the onset and spatio-temporal (location and time) evolution of seizures and the presence of status epilepticus.
Absence seizures are generalized epileptic seizures that can be divided into two types, typical and atypical. Typical and atypical absence seizures display two different kinds of spike-and-wave patterns. Typical absence seizures are described by generalized spike-and-wave patterns on an EEG with a discharge of 2.5 Hz or greater.
If several million neurons discharge at once, it shows up on a scalp EEG as a focal interictal epileptiform spike. Paroxysmal depolarizing shifts can lead to an epileptic seizure if there is an underlying predisposition, and recording the spike can be an important aid in distinguishing seizure types. [citation needed]
A paper published in 2023 showed that burst suppression and epilepsy may share the same ephaptic coupling mechanism. [6] When inhibitory control is sufficiently low, as in the case of certain general anesthetics such as sevoflurane (due to a decrease in the firing of interneurons [7]), electric fields are able to recruit neighboring cells to fire synchronously, in a burst suppression pattern.
Changes that occur during epileptogenesis are poorly understood but are thought to include cell death, axonal sprouting, reorganization of neural networks, alterations in the release of neurotransmitters, and neurogenesis. [5] These changes cause neurons to become hyperexcitable and can lead to spontaneous seizures. [5]
A seizure is a sudden change in behavior, movement or consciousness due to abnormal electrical activity in the brain. [3] [6] Seizures can look different in different people.. It can be uncontrolled shaking of the whole body (tonic-clonic seizures) or a person spacing out for a few seconds (absence seizure
An electroencephalogram (EEG) is an electrical recording of the activity of the brain taken from the scalp. An EEG can be used to diagnose seizures , sleep disorders , and for monitoring of level of anesthesia during surgery.
It may be used in patients with epilepsy not responding to medical treatment, and who are potential candidates to receive brain surgery in order to control seizures. This technique was introduced in the diagnostic work up of patients with epilepsy by the group of the S. Anne Hospital, Paris, France, in the second half of the 20th century. [ 1 ]
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