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Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. [4] The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). [ 4 ]
Apremilast, a phthalimide derivative that was approved by the U.S. FDA in March 2014 for use as a treatment for psoriatic arthritis, [21] and in September 2014 for the treatment of plaque psoriasis under the brand name Otezla. [22] Cilomilast, in clinical development by GlaxoSmithKline for treatment of COPD. [23]
Roflumilast, sold under the brand name Daxas among others, is a medication used for the treatment of chronic obstructive pulmonary disease, [4] plaque psoriasis, [5] seborrheic dermatitis, [6] and atopic dermatitis. [5]
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Apremilast. PubMed provides review articles from the past five years (limit to free review articles)
Ibudilast has bronchodilator, vasodilator [10] and neuroprotective effects, [11] [12] and is mainly used in the treatment of asthma and stroke. [13] It inhibits platelet aggregation, [14] and may also be useful in the treatment of multiple sclerosis.
Deucravacitinib, sold under the brand name Sotyktu, is a medication used for the treatment of moderate-to-severe plaque psoriasis. [7] It is a tyrosine kinase 2 (TYK2) inhibitor and it is taken by mouth. [7]
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